One of the most challenging, and rewarding, reads in a long time. A masterpiece where every sentence folds in on itself two or three times. Having read Middlesex previously, I was shocked at the similarities in theme and structure, and it was too close to be a ripoff, so I think that book must be an homage to this one.
The history was more engaging than the modern crime aspect (which was actually the central storyline of the book). The most interesting idea is that Joseph Smith encouraged laymen in the church to receive their own personal revelations more so than in other faiths, and that contributes to the regular fracturing of Mormon sects. Not a comprehensive history, but worthwhile.
Excellent exploration of the life of the main character and his/her coming to terms with being a hermaphrodite. The gender relations are obviously the main attraction, and are well done, but so are the family relations and the historical backdrop.
The theme of standing in the middle between two apparently distinct poles is revisited throughout. The most interesting for me was the position of the Greek immigrant (or 2nd generation) in the middle of racially-divided and explosive Detroit. Really well done without beating the reader over the head with metaphor.
Also happens to contain the best and most accurate descriptions of northern Michigan in the summer that I've read.