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Chiefly a record of the descendants of brothers Alexander Clarke and Jeremiah Clark. Alexander was born ca. 1725 and died about 1782. He married Joannah May, who was born in 1740 and died after 1838. Jeremiah was born ca. 1739 and died ca. 1780. He married Nancy Ann, who was born ca. 1743 and died 8 Nov 1836. Alexander and Joannah were the parents of nine children. Jeremiah and Nancy were the parents of seven children. Descendants of these men lived in Virginia, Kentucky, Mississippi, North Carolina, and elsewhere.