Fantasy/ scifi with really tough worlds, where everything is stacked against the main character?

No YA, pls, I'm too old for this sh... stuff! :) Some examples of what I mean: Baru Cormorant, Book of the New Sun, Broken Earth, Winter Road, Blood Song, Witcher, Xenogenesis, Th1rte3n, Priest of Bones, Left Hand of Darkness.